Nanodiamond Particles to Cope with Antibiotic Drug Resistance

Bacteria have unique capabilities that enables them to interplay with microorganisms within human body and escape human immune system, and improve antibiotic drug resistance of bacteria, a direct result from which would be infection based upon bacteria biofilm is hardly eradicated. What's worse, using antibiotics in the long run will generate drug resistance to emerging bacteria microorganism antibiotics, which poses further threat to bacteria biofilm infection.

With the continual progress in nano technology, it has been increasing applied in modern medical sciences, such as probes in nano-imaging technologies and nano drug carrier with targeting. €200,000 has been invested by EU 7th Frame Plan FP7) to form the European PHOTORELEASE R&D Team, composed of nanomedicine scientific researchers from France, the U.K, and Spain. The team takes advantages of inertia, biological compatibility, and the specialty of easy to realize functional engineering design based on demand, of nanodiamond particles and adopts non-biocidal engineering design to cope with bacteria microfilm's drug resistance.

Currently, the research team has made some active progress. By making the best of nanodiamond particle anti-adhesive molecules, the interplay of bacteria microorganisms can be prevented effectively, and the expected cure effect for biofilm infection are achieved. This technology is also available to be applied in all kinds of medical device surface to eliminate bacteria microorgamisms.

The research team has succeeded in developing sugar coated nanodiamond particle inhibitors to prevent formation of escherichia coli-based biofilms. After trials and error, functions of nanodiamond particles have been rectified and optimized to assist actual effects of biofilms.